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A novel quantitative trait locus on mouse chromosome 18, "era1," modifies the entrainment of circadian rhythms.

Author
Abstract
:

The mammalian circadian clock in the suprachiasmatic nuclei (SCN) of the hypothalamus conveys 24-h rhythmicity to sleep-wake cycles, locomotor activity, and other behavioral and physiological processes. The timing of rhythms relative to the light/dark (LD12:12) cycle is influenced in part by the endogenous circadian period and the time of day specific sensitivity of the clock to light. We now describe a novel circadian rhythm phenotype, and a locus influencing that phenotype, in a segregating population of mice.

Year of Publication
:
2007
Journal
:
Sleep
Volume
:
30
Issue
:
10
Number of Pages
:
1255-63
ISSN Number
:
0161-8105
URL
:
https://academic.oup.com/sleep/article-lookup/doi/10.1093/sleep/30.10.1255
DOI
:
10.1093/sleep/30.10.1255
Short Title
:
Sleep
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