Dexmedetomidine reduces lipopolysaccharide induced neuroinflammation, sickness behavior, and anhedonia.
| Author | |
|---|---|
| Abstract |
:
Peripheral innate immune response may induce sickness behavior through activating microglia, excessive cytokines production, and neuroinflammation. Dexmedetomidine (Dex) has anti-inflammatory effect. We investigated the effects of Dex on lipopolysaccharide (LPS)-induced neuroinflammation and sickness behavior in mice. |
| Year of Publication |
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0
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| Journal |
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PloS one
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| Volume |
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13
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| Issue |
:
1
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| Number of Pages |
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e0191070
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| Date Published |
:
2018
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| URL |
:
http://dx.plos.org/10.1371/journal.pone.0191070
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| DOI |
:
10.1371/journal.pone.0191070
|
| Short Title |
:
PLoS One
|
| Download citation |
