Evolution of cytogenetically normal acute myeloid leukemia during therapy and relapse: An exome sequencing study of 50 patients.

Author
:
PA Greif
L Hartmann
S Vosberg
S Stief
R Mattes
I Hellmann
KH Metzeler
T Herold
S Bamopoulos
P Kerbs
Jurinovic V
D Schumacher
F Pastore
K Bräundl
E Zellmeier
B Ksienzyk
N Konstandin
S Schneider
A Graf
S Krebs
H Blum
M Neumann
C Baldus
SK Bohlander
S Wolf
D Goerlich
WE Berdel
BJ Woermann
W Hiddemann
K Spiekermann
Abstract
:

To study mechanisms of therapy-resistance and disease progression, we analyzed the evolution of cytogenetically normal acute myeloid leukemia (CN-AML) based on somatic alterations.
Year of Publication
:
2018
Journal
:
Clinical cancer research : an official journal of the American Association for Cancer Research
Date Published
:
2018
ISSN Number
:
1078-0432
URL
:
http://clincancerres.aacrjournals.org/cgi/pmidlookup?view=long&pmid=29330206
DOI
:
10.1158/1078-0432.CCR-17-2344
Short Title
:
Clin Cancer Res
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