Skip to main content

Role of germline aberrations affecting <i>CTNNA1</i>, <i>MAP3K6</i> and <i>MYD88</i> in gastric cancer susceptibility.

Author
Abstract
:

In approximately 10% of all gastric cancer (GC) cases, a heritable cause is suspected. A subset of these cases have a causative germline CDH1 mutation; however, in most cases the cause remains unknown. Our objective was to assess to what extent these remaining cases may be explained by germline mutations in the novel candidate GC predisposing genes CTNNA1, MAP3K6 or MYD88.

Year of Publication
:
2018
Journal
:
Journal of medical genetics
Date Published
:
2018
ISSN Number
:
0022-2593
URL
:
http://jmg.bmj.com/cgi/pmidlookup?view=long&pmid=29330337
DOI
:
10.1136/jmedgenet-2017-104962
Short Title
:
J Med Genet
Download citation