Reduction of hyaluronan and increased expression of HYBID (KIAA1199) correlate with clinical symptoms in photoaged skin.
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Abstract |
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Hyaluronan (HA) metabolism in skin fibroblasts is mediated by HYBID (HYaluronan Binding protein Involved in hyaluronan Depolymerisation, KIAA1199) and HA synthases 1/2 (HAS1/2). However, photoageing-dependent changes in HA and their molecular mechanisms, and the relationship between HA metabolism and clinical symptoms in photoaged skin remain elusive. |
Year of Publication |
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2018
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Journal |
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The British journal of dermatology
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Date Published |
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2018
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ISSN Number |
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0007-0963
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URL |
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http://dx.doi.org/10.1111/bjd.16335
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DOI |
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10.1111/bjd.16335
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Short Title |
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Br J Dermatol
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