A Genetic Investigation of Sex Bias in the Prevalence of Attention-Deficit/Hyperactivity Disorder.

Author
:
J Martin
RK Walters
D Demontis
M Mattheisen
SH Lee
E Robinson
I Brikell
L Ghirardi
H Larsson
P Lichtenstein
N Eriksson
Team. Research
Subgroup. ADHD
Workgroup. ADHD
T Werge
PB Mortensen
MG Pedersen
O Mors
M Nordentoft
DM Hougaard
J Bybjerg-Grauholm
NR Wray
B Franke
SV Faraone
MC O'Donovan
A Thapar
AD Børglum
BM Neale
Abstract
:

Attention-deficit/hyperactivity disorder (ADHD) shows substantial heritability and is two to seven times more common in male individuals than in female individuals. We examined two putative genetic mechanisms underlying this sex bias: sex-specific heterogeneity and higher burden of risk in female cases.
Year of Publication
:
2017
Journal
:
Biological psychiatry
Date Published
:
2017
ISSN Number
:
0006-3223
DOI
:
10.1016/j.biopsych.2017.11.026
Short Title
:
Biol Psychiatry
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