Naltrexone + Bupropion Combination for the Treatment of Binge-eating Disorder with Obesity: A Randomized, Controlled Pilot Study.
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Abstract |
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Binge-eating disorder (BED), the most prevalent eating disorder, is associated strongly with obesity and functional impairments. Few evidence-based treatments for BED exist; a pharmacotherapy effective in reducing both binge eating and weight needs to be identified. This placebo-controlled double-blind pilot RCT evaluated the acute effects of naltrexone + bupropion (NB) on BED with obesity and examined the longer-term effects through 6-month follow-up after the discontinuation of medication. |
Year of Publication |
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2021
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Journal |
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Clinical therapeutics
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Volume |
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43
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Issue |
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1
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Number of Pages |
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112-122.e1
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ISSN Number |
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0149-2918
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URL |
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https://linkinghub.elsevier.com/retrieve/pii/S0149-2918(20)30478-1
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DOI |
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10.1016/j.clinthera.2020.10.010
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Short Title |
:
Clin Ther
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