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Naltrexone + Bupropion Combination for the Treatment of Binge-eating Disorder with Obesity: A Randomized, Controlled Pilot Study.

Author
Abstract
:

Binge-eating disorder (BED), the most prevalent eating disorder, is associated strongly with obesity and functional impairments. Few evidence-based treatments for BED exist; a pharmacotherapy effective in reducing both binge eating and weight needs to be identified. This placebo-controlled double-blind pilot RCT evaluated the acute effects of naltrexone + bupropion (NB) on BED with obesity and examined the longer-term effects through 6-month follow-up after the discontinuation of medication.

Year of Publication
:
2021
Journal
:
Clinical therapeutics
Volume
:
43
Issue
:
1
Number of Pages
:
112-122.e1
ISSN Number
:
0149-2918
URL
:
https://linkinghub.elsevier.com/retrieve/pii/S0149-2918(20)30478-1
DOI
:
10.1016/j.clinthera.2020.10.010
Short Title
:
Clin Ther
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