Effects of ethanol, naltrexone, nicotine and varenicline in an ethanol and nicotine co-use model in Sprague-Dawley rats.
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Abstract |
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As alcohol and nicotine use disorders are entwined, it may be possible to develop a single medication to treat both. We previously developed a model for ethanol (EtOH) and nicotine co-use in female selectively bred alcohol-preferring (P) rats. To model co-use in a genetically diverse population, we adapted the model to outbred Sprague-Dawley rats of both sexes and assessed the effect of drug pretreatments. |
Year of Publication |
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2020
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Journal |
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Drug and alcohol dependence
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Volume |
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212
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Number of Pages |
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107988
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Date Published |
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2020
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ISSN Number |
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0376-8716
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URL |
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https://linkinghub.elsevier.com/retrieve/pii/S0376-8716(20)30153-8
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DOI |
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10.1016/j.drugalcdep.2020.107988
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Short Title |
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Drug Alcohol Depend
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