Coplanar polychlorinated biphenyls impair glucose homeostasis in lean C57BL/6 mice and mitigate beneficial effects of weight loss on glucose homeostasis in obese mice.
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Abstract |
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Previous studies demonstrated that coplanar polychlorinated biphenyls (PCBs) promote proinflammatory gene expression in adipocytes. PCBs are highly lipophilic and accumulate in adipose tissue, a site of insulin resistance in persons with type 2 diabetes. |
Year of Publication |
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2013
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Journal |
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Environmental health perspectives
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Volume |
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121
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Issue |
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1
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Number of Pages |
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105-10
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ISSN Number |
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0091-6765
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URL |
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https://ehp.niehs.nih.gov/doi/10.1289/ehp.1205421?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%3dpubmed
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DOI |
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10.1289/ehp.1205421
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Short Title |
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Environ Health Perspect
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