Fetal intracranial hemorrhage due to maternal subclinical vitamin K deficiency associated with long-term eating disorder.
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| Abstract | :  Vitamin K deficiency in pregnant women causes intracranial hemorrhage (ICH) in fetuses. Fetal ICH frequently causes life-threatening and persistent neurological damage. However, indicators for preventing fetal ICH are not established. Two pregnant women developed long-term eating disorders caused by psychosis. They were administered intravenous fluid and vitamin supplementation, excluding vitamin K. The intracranial low-hypoechoic area on fetal ultrasound was suggestive of fetal ICH due to vitamin K deficiency. Their neonates showed severe developmental delay. Laboratory analysis revealed a normal prothrombin time, but elevated protein induced by vitamin K absence II. Pregnant women who have eating disorders more than 3 weeks could develop fetal ICH due to maternal subclinical vitamin K deficiency. Illness duration and protein induced by vitamin K absence II of pregnant woman may be indicators for vitamin K administration to prevent fetal intracranial hemorrhage. | 
| Year of Publication | :  2019 | 
| Journal | :  The journal of obstetrics and gynaecology research | 
| Volume | :  45 | 
| Issue | :  2 | 
| Number of Pages | :  461-465 | 
| ISSN Number | :  1341-8076 | 
| URL | :  https://doi.org/10.1111/jog.13825 | 
| DOI | :  10.1111/jog.13825 | 
| Short Title | :  J Obstet Gynaecol Res | 
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