Studies on the development of ¹⁶⁹Yb-brachytherapy seeds: New generation brachytherapy sources for the management of cancer.
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| Abstract | :  This paper describes development of (169)Yb-seeds by encapsulating 0.6-0.65 mm (ϕ) sized (169)Yb2O3 microspheres in titanium capsules. Microspheres synthesized by a sol-gel route were characterized by XRD, SEM/EDS and ICP-AES. Optimization of neutron irradiation was accomplished and (169)Yb-seeds up to 74 MBq of (169)Yb could be produced from natural Yb2O3 microspheres, which have the potential for use in prostate brachytherapy. A protocol to prepare (169)Yb-brachytherapy sources (2.96-3.7 TBq of (169)Yb) with the use of enriched targets was also formulated. | 
| Year of Publication | :  2015 | 
| Journal | :  Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine | 
| Volume | :  101 | 
| Number of Pages | :  75-82 | 
| ISSN Number | :  0969-8043 | 
| URL | :  https://linkinghub.elsevier.com/retrieve/pii/S0969-8043(15)00098-6 | 
| DOI | :  10.1016/j.apradiso.2015.03.020 | 
| Short Title | :  Appl Radiat Isot | 
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