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Do high fasting glucose levels suggest nocturnal hypoglycaemia? The Somogyi effect-more fiction than fact?

Author
Abstract
:

The Somogyi effect postulates that nocturnal hypoglycaemia causes fasting hyperglycaemia attributable to counter-regulatory hormone release. Although most published evidence has failed to support this hypothesis, this concept remains firmly embedded in clinical practice and often prevents patients and professionals from optimizing overnight insulin. Previous observational data found lower fasting glucose was associated with nocturnal hypoglycaemia, but did not assess the probability of infrequent individual episodes of rebound hypoglycaemia. We analysed continuous glucose monitoring data to explore its prevalence.

Year of Publication
:
2013
Journal
:
Diabetic medicine : a journal of the British Diabetic Association
Volume
:
30
Issue
:
8
Number of Pages
:
914-7
ISSN Number
:
0742-3071
URL
:
https://doi.org/10.1111/dme.12175
DOI
:
10.1111/dme.12175
Short Title
:
Diabet Med
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