Compromised JMJD6 histone demethylase activity impacts on VHL gene repression in preeclampsia.
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Abstract |
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The von Hippel Lindau (VHL) protein is a key executor of the cellular hypoxic response that is compromised in preeclampsia, a serious disorder complicating 5-7% of pregnancies. To date, the mechanisms controlling VHL gene expression in the human placenta remain elusive. |
Year of Publication |
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2018
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Journal |
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The Journal of clinical endocrinology and metabolism
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Date Published |
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2018
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ISSN Number |
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0021-972X
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DOI |
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10.1210/jc.2017-02197
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Short Title |
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J Clin Endocrinol Metab
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