Farnesoid X receptor antagonist exacerbates dyslipidemia in mice.
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Abstract |
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The effects of farnesoid X receptor (FXR) antagonists on plasma lipid profile in mice have not been investigated thus far. The aim of this study was to investigate the antidyslipidemic effects of an FXR antagonist in dyslipidemic mice, and to clarify the mechanisms underlying the lipid modulatory effect. |
Year of Publication |
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2017
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Journal |
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Pharmacological reports : PR
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Volume |
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70
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Issue |
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1
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Number of Pages |
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172-177
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Date Published |
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2017
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ISSN Number |
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1734-1140
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URL |
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http://linkinghub.elsevier.com/retrieve/pii/S1734-1140(17)30091-9
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DOI |
:
10.1016/j.pharep.2017.07.010
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Short Title |
:
Pharmacol Rep
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