Beyond pairwise distances: neighbor-joining with phylogenetic diversity estimates.
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Abstract |
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The "neighbor-joining algorithm" is a recursive procedure for reconstructing trees that is based on a transformation of pairwise distances between leaves. We present a generalization of the neighbor-joining transformation, which uses estimates of phylogenetic diversity rather than pairwise distances in the tree. This leads to an improved neighbor-joining algorithm whose total running time is still polynomial in the number of taxa. On simulated data, the method outperforms other distance-based methods. We have implemented neighbor-joining for subtree weights in a program called MJOIN which is freely available under the Gnu Public License at http://bio.math.berkeley.edu/mjoin/. |
Year of Publication |
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2006
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Journal |
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Molecular biology and evolution
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Volume |
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23
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Issue |
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3
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Number of Pages |
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491-8
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ISSN Number |
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0737-4038
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URL |
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https://academic.oup.com/mbe/article-lookup/doi/10.1093/molbev/msj059
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DOI |
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10.1093/molbev/msj059
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Short Title |
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Mol Biol Evol
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