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Vaginal dysbiosis increases risk of preterm fetal membrane rupture, neonatal sepsis and is exacerbated by erythromycin.

Author
Abstract
:

Preterm prelabour rupture of the fetal membranes (PPROM) precedes 30% of preterm births and is a risk factor for early onset neonatal sepsis. As PPROM is strongly associated with ascending vaginal infection, prophylactic antibiotics are widely used. The evolution of vaginal microbiota compositions associated with PPROM and the impact of antibiotics on bacterial compositions are unknown.

Year of Publication
:
2018
Journal
:
BMC medicine
Volume
:
16
Issue
:
1
Number of Pages
:
9
Date Published
:
2018
URL
:
https://bmcmedicine.biomedcentral.com/articles/10.1186/s12916-017-0999-x
DOI
:
10.1186/s12916-017-0999-x
Short Title
:
BMC Med
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