Neither non-toxigenic <i>Staphylococcus aureus</i> nor commensal <i>S. epidermidi</i> activates NLRP3 inflammasomes in human conjunctival goblet cells.
Author | |
---|---|
Abstract |
:
The conjunctiva is a wet mucosal surface surrounding the cornea that is continuously exposed to pathogens. Nevertheless, persistent inflammation is not observed. We examined if the NOD-like receptor pyrin domain 3 (NLRP3) inflammasome functions as a sensor that distinguishes commensal and non-pathogenic bacteria from pathogenic bacteria in human conjunctival goblet cells. |
Year of Publication |
:
0
|
Journal |
:
BMJ open ophthalmology
|
Volume |
:
2
|
Issue |
:
1
|
Number of Pages |
:
e000101
|
Date Published |
:
2017
|
DOI |
:
10.1136/bmjophth-2017-000101
|
Short Title |
:
BMJ Open Ophthalmol
|
Download citation |