The Jun/miR-22/HuR regulatory axis contributes to tumourigenesis in colorectal cancer.
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Abstract |
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Colorectal cancer (CRC) is a severe health problem worldwide. Clarifying the mechanisms for the deregulation of oncogenes and tumour suppressors in CRC is vital for its diagnosis, treatment, prognosis and prevention. Hu antigen R (HuR), which is highly upregulated in CRC, functions as a pivotal oncogene to promote CRC progression. However, the underlying cause of its dysregulation is poorly understood. |
Year of Publication |
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2018
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Journal |
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Molecular cancer
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Volume |
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17
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Issue |
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1
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Number of Pages |
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11
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Date Published |
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2018
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URL |
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https://molecular-cancer.biomedcentral.com/articles/10.1186/s12943-017-0751-3
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DOI |
:
10.1186/s12943-017-0751-3
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Short Title |
:
Mol Cancer
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