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Surgical damage to the lymphatic system promotes tumor growth via impaired adaptive immune response.

Author
Abstract
:

Both lymph nodes (LNs) and lymphatic channels from primary sites to regional LNs are critical for initiation of adaptive immunity. However, as LNs are common metastatic sites in skin cancers, LN biopsies or dissections are frequently performed. In addition, reconstructive skin flaps after tumor resection may damage lymphatic flow from primary sites to regional LNs.

Year of Publication
:
2017
Journal
:
Journal of dermatological science
Date Published
:
2017
ISSN Number
:
0923-1811
URL
:
http://linkinghub.elsevier.com/retrieve/pii/S0923-1811(17)31020-4
DOI
:
10.1016/j.jdermsci.2017.12.016
Short Title
:
J Dermatol Sci
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