Sharma, A. ., Subudhi, S. ., Blando, J. ., Scutti, J. ., Vence, L. ., Wargo, J. ., … Sharma, P. . (2018). Anti-CTLA-4 immunotherapy does not deplete FOXP3+ regulatory T cells (Tregs) in human cancers. Clinical Cancer Research : An Official Journal of the American Association for Cancer Research. https://doi.org/10.1158/1078-0432.CCR-18-0762 (Original work published 2018)
JA Wargo
First name:
JA
Last name:
Wargo
Amaria, R. ., Prieto, P. ., Tetzlaff, M. ., Reuben, A. ., Andrews, M. ., Ross, M. ., … Wargo, J. . (2018). Neoadjuvant plus adjuvant dabrafenib and trametinib versus standard of care in patients with high-risk, surgically resectable melanoma: a single-centre, open-label, randomised, phase 2 trial. The Lancet. Oncology, 19(2), 181-193. https://doi.org/10.1016/S1470-2045(18)30015-9
, Spencer, C. ., Nezi, L. ., Reuben, A. ., Andrews, M. ., Karpinets, T. ., … Wargo, J. . (2018). Gut microbiome modulates response to anti-PD-1 immunotherapy in melanoma patients. Science (New York, N.Y.), 359(6371), 97-103. https://doi.org/10.1126/science.aan4236 (Original work published 2018)
Reuben, A. ., Spencer, C. ., Prieto, P. ., , Reddy, S. ., Miller, J. ., … Wargo, J. . Genomic and immune heterogeneity are associated with differential responses to therapy in melanoma. NPJ Genomic Medicine, 2. https://doi.org/10.1038/s41525-017-0013-8 (Original work published 2017)
Wei, S. ., Levine, J. ., Cogdill, A. ., Zhao, Y. ., Anang, N. ., Andrews, M. ., … Allison, J. . (2017). Distinct Cellular Mechanisms Underlie Anti-CTLA-4 and Anti-PD-1 Checkpoint Blockade. Cell, 170(6), 1120-1133.e17. https://doi.org/10.1016/j.cell.2017.07.024 (Original work published 2017)
Reuben, A. ., Gittelman, R. ., Gao, J. ., Zhang, J. ., Yusko, E. ., Wu, C. ., … Zhang, J. . (2017). TCR Repertoire Intratumor Heterogeneity in Localized Lung Adenocarcinomas: An Association with Predicted Neoantigen Heterogeneity and Postsurgical Recurrence. Cancer Discovery, 7(10), 1088-1097. https://doi.org/10.1158/2159-8290.CD-17-0256
Roh, W. ., Chen, P. ., Reuben, A. ., Spencer, C. ., Prieto, P. ., Miller, J. ., … Futreal, P. . (2017). Integrated molecular analysis of tumor biopsies on sequential CTLA-4 and PD-1 blockade reveals markers of response and resistance. Science Translational Medicine, 9(379). https://doi.org/10.1126/scitranslmed.aah3560 (Original work published 2017)