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Barone, E. ., Di Domenico, F. ., Cassano, T. ., Arena, A. ., Tramutola, A. ., Lavecchia, M. ., … Perluigi, M. . (2016). Impairment of biliverdin reductase-A promotes brain insulin resistance in Alzheimer disease: A new paradigm. Free Radical Biology & Medicine, 91, 127-42. https://doi.org/10.1016/j.freeradbiomed.2015.12.012

Tramutola, A. ., Di Domenico, F. ., Barone, E. ., Perluigi, M. ., & Butterfield, D. . It Is All about (U)biquitin: Role of Altered Ubiquitin-Proteasome System and UCHL1 in Alzheimer Disease. Oxidative Medicine and Cellular Longevity, 2016, 2756068. https://doi.org/10.1155/2016/2756068 (Original work published 2016)

Tramutola, A. ., Pupo, G. ., Di Domenico, F. ., Barone, E. ., Arena, A. ., Lanzillotta, C. ., … Perluigi, M. . Activation of p53 in Down Syndrome and in the Ts65Dn Mouse Brain is Associated with a Pro-Apoptotic Phenotype. Journal of Alzheimer’s Disease : JAD, 52(1), 359-371. https://doi.org/10.3233/JAD-151105 (Original work published 2016)

Di Domenico, F. ., Tramutola, A. ., Barone, E. ., Lanzillotta, C. ., Defever, O. ., Arena, A. ., … Perluigi, M. . (2019). Restoration of aberrant mTOR signaling by intranasal rapamycin reduces oxidative damage: Focus on HNE-modified proteins in a mouse model of down syndrome. Redox Biology, 23, 101162. https://doi.org/10.1016/j.redox.2019.101162

Di Domenico, F. ., Tramutola, A. ., Foppoli, C. ., Head, E. ., Perluigi, M. ., & Butterfield, D. . (2018). mTOR in Down syndrome: Role in Aß and tau neuropathology and transition to Alzheimer disease-like dementia. Free Radical Biology & Medicine, 114, 94-101. https://doi.org/10.1016/j.freeradbiomed.2017.08.009

Di Domenico, F. ., Pupo, G. ., Tramutola, A. ., Giorgi, A. ., Schininà, M. ., Coccia, R. ., … Perluigi, M. . (2014). Redox proteomics analysis of HNE-modified proteins in Down syndrome brain: clues for understanding the development of Alzheimer disease. Free Radical Biology & Medicine, 71, 270-280. https://doi.org/10.1016/j.freeradbiomed.2014.03.027

Perluigi, M. ., Pupo, G. ., Tramutola, A. ., Cini, C. ., Coccia, R. ., Barone, E. ., … Di Domenico, F. . (2014). Neuropathological role of PI3K/Akt/mTOR axis in Down syndrome brain. Biochimica Et Biophysica Acta, 1842(7), 1144-53. https://doi.org/10.1016/j.bbadis.2014.04.007

Triplett, J. ., Tramutola, A. ., Swomley, A. ., Kirk, J. ., Grimes, K. ., Lewis, K. ., … Butterfield, D. . (2015). Age-related changes in the proteostasis network in the brain of the naked mole-rat: Implications promoting healthy longevity. Biochimica Et Biophysica Acta, 1852(10 Pt A), 2213-24. https://doi.org/10.1016/j.bbadis.2015.08.002

Di Domenico, F. ., Pupo, G. ., Giraldo, E. ., Badìa, M. ., Monllor, P. ., Lloret, A. ., … Perluigi, M. . (2016). Oxidative signature of cerebrospinal fluid from mild cognitive impairment and Alzheimer disease patients. Free Radical Biology & Medicine, 91, 1-9. https://doi.org/10.1016/j.freeradbiomed.2015.12.004