Lanzillotta, C. ., Di Domenico, F. ., Perluigi, M. ., & Butterfield, D. . (2019). Targeting Mitochondria in Alzheimer Disease: Rationale and Perspectives. CNS Drugs, 33(10), 957-969. https://doi.org/10.1007/s40263-019-00658-8

Di Domenico, F. ., Tramutola, A. ., Barone, E. ., Lanzillotta, C. ., Defever, O. ., Arena, A. ., … Perluigi, M. . (2019). Restoration of aberrant mTOR signaling by intranasal rapamycin reduces oxidative damage: Focus on HNE-modified proteins in a mouse model of down syndrome. Redox Biology, 23, 101162. https://doi.org/10.1016/j.redox.2019.101162

Sharma, N. ., Tramutola, A. ., Lanzillotta, C. ., Arena, A. ., Blarzino, C. ., Cassano, T. ., … Barone, E. . (2019). Loss of biliverdin reductase-A favors Tau hyper-phosphorylation in Alzheimer’s disease. Neurobiology of Disease, 125, 176-189. https://doi.org/10.1016/j.nbd.2019.02.003

Tramutola, A. ., Lanzillotta, C. ., Barone, E. ., Arena, A. ., Zuliani, I. ., Mosca, L. ., … Di Domenico, F. . Intranasal rapamycin ameliorates Alzheimer-like cognitive decline in a mouse model of Down syndrome. Translational Neurodegeneration, 7, 28. https://doi.org/10.1186/s40035-018-0133-9 (Original work published 2018)

Tramutola, A. ., Abate, G. ., Lanzillotta, C. ., Triani, F. ., Barone, E. ., Iavarone, F. ., … Uberti, D. . (2018). Protein nitration profile of CD3⁺ lymphocytes from Alzheimer disease patients: Novel hints on immunosenescence and biomarker detection. Free Radical Biology & Medicine, 129, 430-439. https://doi.org/10.1016/j.freeradbiomed.2018.10.414

Tramutola, A. ., Sharma, N. ., Barone, E. ., Lanzillotta, C. ., Castellani, A. ., Iavarone, F. ., … Di Domenico, F. . (2018). Proteomic identification of altered protein O-GlcNAcylation in a triple transgenic mouse model of Alzheimer’s disease. Biochimica Et Biophysica Acta. Molecular Basis of Disease, 1864(10), 3309-3321. https://doi.org/10.1016/j.bbadis.2018.07.017

Tramutola, A. ., Lanzillotta, C. ., Perluigi, M. ., & Butterfield, D. . (2017). Oxidative stress, protein modification and Alzheimer disease. Brain Research Bulletin, 133, 88-96. https://doi.org/10.1016/j.brainresbull.2016.06.005

Tramutola, A. ., Pupo, G. ., Di Domenico, F. ., Barone, E. ., Arena, A. ., Lanzillotta, C. ., … Perluigi, M. . Activation of p53 in Down Syndrome and in the Ts65Dn Mouse Brain is Associated with a Pro-Apoptotic Phenotype. Journal of Alzheimer’s Disease : JAD, 52(1), 359-371. https://doi.org/10.3233/JAD-151105 (Original work published 2016)

Tramutola, A. ., Lanzillotta, C. ., Di Domenico, F. ., Head, E. ., Butterfield, D. ., Perluigi, M. ., & Barone, E. . (2020). Brain insulin resistance triggers early onset Alzheimer disease in Down syndrome. Neurobiology of Disease, 137, 104772. https://doi.org/10.1016/j.nbd.2020.104772

Lanzillotta, C. ., Zuliani, I. ., Tramutola, A. ., Barone, E. ., Blarzino, C. ., , … Di Domenico, F. . (2021). Chronic PERK induction promotes Alzheimer-like neuropathology in Down syndrome: Insights for therapeutic intervention. Progress in Neurobiology, 196, 101892. https://doi.org/10.1016/j.pneurobio.2020.101892